LOE is short for Letter of explanation. I believe what
@anwar01 has suggested is that Whatever changes you have made in your EE profile you can explain the same in the letter of explanation section while completing your application that you're about to submit with OINP.
And yes OINP does check the EE profile and details filled in it while processing your application under OINP so if there is a mismatch of any nature or any changes have been made at any stage, for whatever reason, do give the details in the letter of explanation for OINP to understand.